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Merge pull request #780 from haddocking/haddock2.5
Updated haddock2.5 version and list of changes
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software/haddock2.4/changes.md

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### Changes - version March 2026 (haddock2.5 only)
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- Added missing improper parameters for NGA glycan
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- Correct bug causing automatic reduction of the cluster size for reclustering to fail
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- Added support for THR glycosylation
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### Changes - version August 2025 (haddock2.5 only)
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- Increased some array size parameters in the provided CNS code
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- Added support for pyro-glutamic acid (PCA)
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- Modified analysis to write stage-specific CNS average job files
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- Simplified CNS execution scripts
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- Added check of coordinates for consistency with the PDB format
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### Changes - version December 2024 (haddock2.5 only)
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- Removed the minimisation of fully flexible regions during topology generation
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- Changed nucleic acid oxygen phosphage naming to OP1/OP2 (inline with PDB naming)
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- Added beta sialic acid (SIB), and additional linkages between glycans
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- Added modified DNA baseJ (DJ)
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- Corrected issue with automatic his protonation state
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- Added automatic definition of restraints to maintain ions in their coordination sphere.
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- Added automatic definition of restraints to maintain ions in their coordination sphere
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- Modified analysis scripts to work with a single ligand molecule
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software/haddock2.4/index.md

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![Structure + Binformatic/Biophysical Data => Complex](HADDOCK2.4.png)
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_Version:_ 2.5 (December 2024) ([changes](/software/haddock2.4/changes))
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_Version:_ 2.5 (March 2026) ([changes](/software/haddock2.4/changes))
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2020
_Authors:_ Alexandre Bonvin and members of the computational structural biology group, Utrecht University
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